Iodine-mediated regioselective C2-amination of indoles and a concise total synthesis of (±)-folicanthine.
نویسندگان
چکیده
Highly substituted 2-aminated indoles can be prepared in moderate to excellent yields by regioselective C2-amination of indoles promoted by iodine. As a key step in a concise synthesis of (±)-folicanthine, its core structure was easily obtained by one step cyclization-dimerization of substituted tryptophan in high yield on a gram scale.
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عنوان ژورنال:
- Chemical communications
دوره 48 17 شماره
صفحات -
تاریخ انتشار 2012